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- Module 6 Overview
Treatment of Key Populations and Unique Situations - 0%Lesson 1
Treatment of HCV in Persons with HIV CoinfectionActivities- 0%Lesson 2
Treatment of HCV in Persons with Renal ImpairmentActivities- 0%Lesson 3
Treatment of HCV in Persons with Substance UseActivities- 0%Lesson 4
Treatment of HCV in a Correctional SettingActivities- 0%Lesson 5
Management of Health Care Personnel Exposed to HCVActivities- 0%Lesson 6
Perinatal HCV TransmissionActivitiesTreatment of Key Populations and Unique Situations Overview4th Edition
Module Core Competency
Apply Evidence-Based HCV Treatment to Key Populations and in Unique Situations
Target Audience
Designed for clinicians who manage key populations of persons living with HCV and/or complex HCV-related unique treatment issues. Material covered is at an advanced level.Editors
H. Nina Kim, MD, MSc,H. Nina Kim, MD, MSc
Professor of Medicine
Division of Allergy & Infectious Diseases
University of WashingtonDisclosures: NoneMaria A. Corcorran, MD, MPHMaria A. Corcorran, MD, MPH
Assistant Professor
Division of Allergy & Infectious Diseases
University of WashingtonDisclosures: NoneFree CNE/CME
Module Lessons
1Lesson 1 Treatment of HCV in Persons with HIV Coinfection
- Learning Objectives
- Explain the impact of HIV on the progression of liver fibrosis in persons with untreated chronic HCV
- Describe current HCV treatment approaches in persons with HIV coinfection
- Discuss HCV treatment responses in persons with HIV and HCV coinfection compared with responses in persons with HCV monoinfection
- Summarize recommendations for treating HIV in persons with HCV and HIV coinfection
- List key drug interactions between HCV direct-acting antivirals and HIV antiretroviral medications
- Quick ReferenceTreatment of HCV in Persons with HIV Coinfection Core Concepts
- Activity 1B.DHHS Guidelines for HCV-HIV Coinfection
2Lesson 2 Treatment of HCV in Persons with Renal Impairment
- Learning Objectives
- Explain the impact of HCV on renal disease
- Summarize the main findings from HCV treatment studies in people with renal disease
- Discuss dosing of direct-acting antiviral medications in persons with chronic renal disease
- Describe appropriate HCV treatment in persons prior to renal transplantaton
- Summarize HCV treatment recommendations in persons following renal transplantation
- Quick ReferenceTreatment of HCV in Persons with Renal Impairment Core Concepts
- Activity 2B.GFR Calculator
3Lesson 3 Treatment of HCV in Persons with Substance Use
- Learning Objectives
- Discuss the prevalence of substance use among persons in the United States
- Describe HCV treatment responses in persons with substance use disorders compared with those who do not have substance use disorders
- Summarize HCV treatment eligibility in persons who have a past or current substance use disorder
- List support services and management strategies for persons with substance use disorders who have chronic HCV infection
- Explain the concept of HCV reinfection in persons who inject drugs
- Quick ReferenceTreatment of HCV in Persons with Substance Use Core Concepts
4Lesson 4 Treatment of HCV in a Correctional Setting
- Learning Objectives
- Describe HCV prevalence in the correctional setting
- Explain the difference between jails and prisons
- Summarize HCV screening recommendations in correctional settings
- State recommendations for HCV treatment eligibility in prisons
- Discuss HCV treatment approach in prisons
- Quick ReferenceTreatment of HCV in a Correctional Setting Core Concepts
5Lesson 5 Management of Health Care Personnel Exposed to HCV
- Learning Objectives
- List the definition of health care personnel
- Estimate the risk of HCV seroconversion after an occupational exposure to HCV that involves a needlestick injury
- Describe management of health care personnel exposed to HCV, based on type and nature of exposure
- Summarize monitoring and follow-up testing of health care personnel after occupational exposure to HCV
- Discuss the treatment approach for health care personnel who acquire HCV from an occupational exposure
- Quick ReferenceManagement of Health Care Personnel Exposed to HCV Core Concepts
6Lesson 6 Perinatal HCV Transmission
- Learning Objectives
- Describe the current guidelines for HCV screening in pregnant women
- Identify the risk of mother-to-child transmission of HCV and factors associated with increased risk of transmission
- Summarize the impact of HCV on pregnancy outcomes
- Describe interventions and/or prophylactic measures to reduce the risk of mother-to-child transmission of HCV
- List recommendations for HCV testing and management in infants born to mothers with HCV.
- Quick ReferencePerinatal HCV Transmission Core Concepts
- Background
- HCV Screening During Pregnancy
- Factors Associated with HCV Perinatal Transmission
- Impact of Chronic HCV Infection on Pregnancy
- Effect of Pregnancy on Chronic HCV
- Interventions to Prevent Mother-to-Child Transmission of HCV
- Safety of HCV Treatment During Pregnancy and Breastfeeding
- Monitoring of Pregnant Women with HCV
- Management of Infants and Children Born to Mothers with HCV Infection
- Summary Points
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- 0%Lesson 2
Funded by
Centers for Disease Control and Prevention Cooperative Agreement (CDC-RFA-PS21-2105)
Created at
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Part of
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CME provided byUniversity of Alabama Birmingham
CNE provided byUniversity of Washington School of Nursing
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